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Duke Nukem: Manhattan Project

Updated v2.0.0.12
Version updated to v2.0.0.12

Updated February 3, 2026 9:50 am (5 months ago)

Duke Nukem: Manhattan Project is a side-scrolling action platformer where you control Duke Nukem as he battles through a virus-turned-monster invasion in New York City. Run, jump, and blast your way across multiple levels, using an arsenal of weapons to save the city from destruction.

ActionAdventurePlatformerShooter
About this game

Duke Nukem: Manhattan Project overview

Gaming’s king of action returns in an all new adventure, this time in New York City. Duke battles his way across towering skyscraper rooftops and through gritty subway stations, hunting for a power-hungry villain, Mech Morphix. Mutants of every kind are thrown at Duke as he chases down Morphix through eight huge environments and avoids the green slime called GLOPP which is causing all the chaos.

But radioactive slime isn’t Duke’s only problem – there are more than 25 uniquely dangerous mutated enemies hell-bent on making a meal of him. Whether it’s Uzi-sporting alligators or ten-foot tall roach beasts – Duke’s in town to blast the bad guys and save the chicks. Sure, pipe bombs, a machine gun, a rocket launcher and a pulse cannon are going to make a goo-filled mess in the Big Apple, but what’s a hero to do?

  • Bombs, gibs, babes and a whole lot of shooting
  • Duke is back with even more ass-kicking awesome one-liners!
  • An intense, fast-paced, action-packed arcade experience
System Requirements

Will this game run on your PC?

Minimum

  • OS: Windows XP or Windows Vista
  • 1.8 GHz Processor
  • 512MB RAM (1 GB recommended)
  • 3D graphics card compatible with DirectX 7 (compatible with DirectX 9 recommended)
  • 2GB HDD
  • Mouse
  • Keyboard.
  • Please be advised that Windows 10 operating system will receive frequent hardware driver and software updates following its release; this may affect game compatibility.
Instructions

Download, Install, and Play

  1. Click the download button to get the link. You’ll be redirected to our link generator.
  2. Once you’re there, you can either copy the link or open it directly.
  3. Download Duke Nukem: Manhattan Project [latest]. Wait until it is 100% complete, then locate the files.
  4. Install the game:
    • Run or double-click setup_********.exe.
    • If a DLC folder is included, run any .exe files inside it as well.
  5. After the installation is complete, launch the game and start playing.
  6. Enjoyed the game? Consider purchasing it from the official store to support the developers.

Need help?
Check our FAQs for common questions and fixes. If you need additional assistance, you can also visit the official GOG Support Center.